The application of food IgG antibody detection in the diagnosis and treatment of allergic diseases
食物IgG抗体检测在过敏性疾病诊治中的应用

摘要

目的 分析在过敏性疾病诊治中应用食物免疫球蛋白G（IgG）抗体检测的临床价值。方法 采集本院2020年1月-2022年1月期间收治的100例过敏性疾病患者，针对入院患者均行食物IgG抗体检测，统计常见10种食物IgG抗体检测阳性率，以及不同性别、年龄段患者食物IgG抗体检测阳性率。结果 100例患者行10种食物IgG抗体检测结果显示，共检出食物IgG抗体检测阳性79例，阳性率为79.00%；其中牛奶IgG抗体检测阳性率最高56.00%，其次为鸡蛋42.00%，再次为大豆24.00%。不同性别患者2种及以上食物IgG抗体检测阳性率比较，男性高于女性57.14%>32.43%（χ2=4.842，P<0.05）。不同年龄段患者食物IgG抗体检测阳性率比较，以1-12岁儿童群体食物IgG抗体检测阳性率最高89.29%，70-79岁老年群体IgG抗体检测阳性率最低33.33%。结论 过敏性疾病的发生与食物不耐受间存在密切关联，且男性、儿童更易发生过敏性疾病；而在过敏性疾病诊治中采取食物IgG抗体检测能够为食物过敏诊断及预防提供积极参考。

Abstract

Objective To analyze the clinical value of using food immunoglobulin G (IgG) antibody detection in the diagnosis and treatment of allergic diseases.
Methods 100 patients with allergic diseases admitted to our hospital from January, 2021 to January, 2022 were collected, and food IgG antibody testing was performed on all admitted patients. The positive rates of IgG antibody testing for 10 common foods, as well as the positive rates of food IgG antibody testing for patients of different genders and age groups, were statistically analyzed.
Results 100 patients were tested for 10 types of food IgG antibodies, and a total of 79 positive cases were detected for food IgG antibodies, with a positive rate of 79.00%; The highest positive rate of IgG antibody detection was 56.00% in milk, followed by 42.00% in eggs, and 24.00% in soybeans. Comparison of positive rates of IgG antibody testing for two or more foods in patients of different genders, with males being 57.14% higher than females, and>32.43% higher than females（χ2=4.842, P<0.05）. The comparison of positive rates of food IgG antibody detection among patients of different age groups shows that the highest positive rate of food IgG antibody detection is 89.29% in children aged 1-12, and the lowest positive rate of IgG antibody detection is 33.33% in the elderly aged 70-79.
Conclusion   There is a close correlation between the occurrence of allergic diseases and food intolerance, and males and children are more likely to develop allergic diseases; The use of food IgG antibody testing in the diagnosis and treatment of allergic diseases can provide positive references for the diagnosis and prevention of food allergies.